Yonago Acta medica 2004;47:4551
Positive Transfer Effect of Amygdaloid Kindling in Developing Rats
Kazuyoshi Matsuda, Shin-ichi Yoshioka, Junji Takasu, Hideaki Mitani and Ryuzo Kawahara
Division of Neuropsychiatry, Department of Multidisciplinary Internal Medicine, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8504 Japan
To study the hypothesis that seizure susceptibility in the young rat brain is higher than that in the adult brain, positive transfer effect (PTE) in amygdaloid kindling in rats was investigated at varing ages: 15 days, 18 days, 28 days, 40 days and 70 days. Although PTE was observed regardless of age, it was more pronounced in weaning rats than in adult rats.
Key words: amygdaloid kindling; development; rat; seizure susceptibility; transfer effect